Scientist (Biologics Cell Line Development)
Asimov
Boston, MA, USA
Posted on Wednesday, April 10, 2024
Our mission at Asimov is to advance humanity's ability to design living systems, enabling biotechnologies with outsized benefit to society. We're developing a mammalian synthetic biology platform––from cells to software––to enable the design and manufacture of next-generation therapeutics.
Asimov, Inc. seeks a full time Scientist at our offices located at 201 Brookline Ave., Boston, MA 02215.
Scientist is a technical expert who will be responsible for conducting CHO-based cell line engineering for biologic therapeutics, designing complex experimental approaches to improve our workflows and systems, coordinating project efforts, and mentoring junior scientists.
Duties include:
- Perform CHO cell line development cell culture processes including transfection, cloning, characterization, and cell banking.
- Perform fed-batch bioreactor analyses on CHO cells
- Perform Octet and HPLC analytical analyses
- Design complex experiments, analyze data, troubleshoot, and maintain detailed records
- Mentor and train junior scientists
- Present scientific data to colleagues and clients, and prepare presentations and summary reports
- Identify emerging practices and drive innovation for biologics cell line development and manufacturing to shape scientific strategies and develop improved workflows.
- Represent the cell line development team on cross-functional projects, making decisions for cell line activities and effectively communicating results, progress and plans.=
Position requirements:
- Master’s degree (or foreign degree equivalent) in Biological Engineering, Biotechnology, Cell Biology, Molecular Biology or closely related field, plus 2 years of experience in any scientist, or related position.
- 2 years of experience working with CHO cell culture
- 2 years of experience maintaining detailed records, such as working within an electronic laboratory notebook
- 1 year of experience titering monoclonal antibodies
- 1 year of cell culture metabolite analysis
- 1 year of research for improving cell line development or process development workflows
- 1 year of experience running bioreactors on CHO cells, including programming, inoculating, harvesting, and troubleshooting
- 1 year of experience with DOE or data analysis software (for example, JMP, MODDE)
- 1 year of experience presenting data and summary slides in team and/or department meetings
- 1 year of experience working with spreadsheets such as Google Sheets or Excel
Experience, which may be gained concurrently, must include the following:
#LI-DNI
We're fueled by a vision to transform biological engineering into a fully-fledged engineering discipline. Should you join our team, you will grow with a constantly evolving organization and push the frontiers of synthetic biology. Company culture is key to Asimov, and ours is a culture of recombination; we believe that our mission can only be achieved by bringing together a diverse team with a mixture of backgrounds and perspectives.